Harmonisierung des Risikomanagements für Einsatz und Outsourcing von Informationstechnologie

Die vorliegende Arbeit stellt ein Integrationsmodell zur Harmonisierung des Risikomanagements für den Einsatz und das Outsourcing von Informationstechnologie vor. Nach der einführenden Darlegung von Kontext, Motivation und Forschungsfrage werden wesentliche Begriffsdefinitionen vorgenommen sowie die Arbeit von bestehenden Werken abgegrenzt. In einem ersten Schritt erfolgt eine umfassende Darstellung der verwendeten Ansätze, die im Rahmen einer objektorientierten Analyse auf inhaltlicher und struktureller Ebene betrachtet werden. In der anschließenden Design-Phase werden die zuvor ermittelten Konzepte gegenübergestellt und bewertet, sowie im finalen Schritt ein Integrationsmodell erarbeitet, welches Begriffs- und Prozessgruppen als UML-Klassen- und Aktivitätsdiagramme definiert. Es findet eine Validierung des Integrationsmodells durch einen Falsifikationsversuch im Sinne des kritischen Rationalismus statt. Eine Zusammenfassung, Schlussfolgerungen und weiterführende Fragestellungen runden die Arbeit ab.This paper presents an integration model to harmonize heterogenous risk management approaches used in IT operations and outsourcing. Having defined the working context, motivation and research question, this paper introduces necessary terms and concepts and distinguishes its core topic from related work. As a first step, the relevant risk management approaches are being described in detail, and their contents and structure are being explored using an object-oriented data-modeling approach. During the design phase, the identified concepts are being compared, evaluated and finally transformed into an integrated UML-based class and activity model containing the necessary groups of terms, definitions and processes. The integration model is validated using an attempt to falsify it in terms of critical rationalism. The paper is concluded by a summary and the deduction of implications as well as questions for further research

Readout system and testbeam results of the RD50-MPW2 HV-CMOS pixel chip

The RD50-CMOS group aims to design and study High Voltage CMOS (HVCMOS) chips for use in a high radiation environment. Currently, measurements are performed on RD50-MPW2 chip, the second prototype developed by this group. The active matrix of the prototype consists of 8x8 pixels with analog front end. Details of the analog front end and simulations have been already published earlier. This contribution focuses on the Caribou based readout system of the active matrix. Each pixel of the active matrix can be readout one after the other. Relevant aspects of hardware, firmware and software are introduced. As a first stage, firmware for a standalone setup is introduced and details on data flow are given. Afterwards, a second stage of the firmware capable of synchronizing with other detectors and accepting triggers is presented, focusing on operation of the chip in combination with a tracking telescope to measure efficiency and residuals.Comment: Published under licence in Journal of Physics: Conference Series by IOP Publishing Ltd. CC-BY Content from this work may be used under the terms of the Creative Commons Attribution 4.0 International licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DO

Material models for highly dynamic metal forming processes

Nowadays, industrial processes like sheet metal bending or punching are performed with high precision. Further optimizations are only possible by simulation and appropriate material models and parameters. Goal of this work is to find a material model suitable for both, bending and punching processes, including the effects of plasticity at high strains and strain rates. The models are calibrated by material tests like tension or torsion tests

RD50-MPW3: A fully monolithic digital CMOS sensor for future tracking detectors

The CERN-RD50 CMOS working group develops the RD50-MPWseries of monolithic high-voltage CMOS pixel sensors for potential use in future high luminosity experiments such as the HL-LHC and FCC-hh. In this contribution, the design of the latest prototype in this series, RD50-MPW3, is presented. An overview of its pixel matrix and digital readout periphery is given, with discussion of the new structures implemented in the chip and the problems they aim to solve. The main analog and digital features of the sensor are already tested and initial laboratory characterisation of the chip is presented

CESTA, a positive regulator of brassinosteroid biosynthesis

Brassinosteroids are important plant hormones involved in the regulation of cell elongation, division, differentiation and development. This study identifies CESTA as a basic helix-loop-helix transcription factor that positively regulates brassinosteroid homeostasis

Internet-based cognitive behavior therapy for obsessive compulsive disorder: A pilot study

<p>Abstract</p> <p>Background</p> <p>Cognitive behavior therapy (CBT) is widely regarded as an effective treatment for obsessive compulsive disorder (OCD), but access to CBT therapists is limited. Internet-based CBT (ICBT) with therapist support is a way to increase access to CBT but has not been developed or tested for OCD. The aim of this study was to evaluate ICBT for OCD.</p> <p>Method</p> <p>An open trial where patients (N = 23) received a 15-week ICBT program with therapist support consisting of psychoeducation, cognitive restructuring and exposure with response prevention. The primary outcome was the Yale-Brown Obsessive Compulsive Scale (Y-BOCS), which was assessed by a psychiatrist before and immediately after treatment. Secondary outcomes were self-rated measures of OCD symptoms, depressive symptoms, general functioning, anxiety and quality of life. All assessments were made at baseline and post-treatment.</p> <p>Results</p> <p>All participants completed the primary outcome measure at all assessment points. There were reductions in OCD symptoms with a large within-group effect size (Cohen's <it>d </it>= 1.56). At post-treatment, 61% of participants had a clinically significant improvement and 43% no longer fulfilled the diagnostic criteria of OCD. The treatment also resulted in statistically significant improvements in self-rated OCD symptoms, general functioning and depression.</p> <p>Conclusions</p> <p>ICBT with therapist support reduces OCD symptoms, depressive symptoms and improves general functioning. Randomized trials are needed to confirm the effectiveness of this new treatment format.</p> <p>Trial Registration</p> <p>ClinicalTrials.gov: <a href="http://www.clinicaltrials.gov/ct2/show/NCT01348529">NCT01348529</a></p

Predictors of binge drinking in adolescents: ultimate and distal factors - a representative study

<p>Abstract</p> <p>Background</p> <p>As epidemiological surveys have shown, binge drinking is a constant and wide-spread problem behavior in adolescents. It is not rare to find that more than half of all adolescents engage in this behavior when assessing only the last 4 weeks of time independent of the urbanity of the region they live in. There have been several reviews on predictors of substance consumption in adolescents in general, but there has been less high quality research on predictors of binge drinking, and most studies have not been theoretically based. The current study aimed to analyze the ultimate and distal factors predicting substance consumption according to Petraitis' theory of triadic influence. We assessed the predictive value of these factors with respect to binge drinking in German adolescents, including the identification of influence direction.</p> <p>Methods</p> <p>In the years 2007/2008, a representative written survey of N = 44,610 students in the 9^thgrade of different school types in Germany was carried out (net sample). The return rate of questionnaires was 88% regarding all students whose teachers or school directors had agreed to participate in the study. In this survey, prevalence of binge drinking was investigated as well as potential predictors from the social/interpersonal, the attitudinal/environmental, and the intrapersonal fields (3 factors of Petraitis). In a multivariate logistic regression analysis, these variables were included after testing for multicollinearity in order to assess their ability to predict binge drinking.</p> <p>Results</p> <p>Prevalence of binge drinking in the last 30 days was 52.3% for the surveyed adolescents with a higher prevalence for boys (56.9%) than for girls (47.5%). The two most influential factors found to protect against binge drinking with <it>p </it>< .001 were low economic status and importance of religion. The four most relevant risk factors for binge drinking (<it>p </it>< .001) were life-time prevalence of school absenteeism/truancy, academic failure, suicidal thoughts, and violence at school in the form of aggressive behavior of teachers. The model of Petraitis was partly confirmed for Binge Drinking in German adolescents and the direction of influence factors was clarified.</p> <p>Conclusions</p> <p>Whereas some of the risk and protective factors for binge drinking are not surprising since they are known for substance abuse in general, there are two points that could be targeted in interventions that do not focus on adolescents alone: (a) training teachers in positive, reassuring behavior and constructive criticism and (b) a focus on high risk adolescents either because they have a lack of coping strategies when in a negative mood or because of their low academic achievement in combination with absenteeism from school.</p